The Vice President will be Latino
Both parties want to get the Latino vote. Rubio will be the Republican VP nominee. Not sure which Castro brother will be the Democratic nominee.
Trump will form a third party
He is getting bored and realizes he can not win even the Republican Nomination so he will get out of the Republican race claiming that the republican establishment has ganged up on him. He will form a third party with his only objective being to get in the national debates like Ross Perot. He will have a female VP candidate running with him. Not sure who.
The Republican Nominee with be Romney
None of the current candidates will a majority in the primaries. Thus, the nomination will go to the convention where Romney will be brokered by the establishment once the delegates are released.
The Democratic Nominee will be Clinton
Sanders is not really a challenge. She has the nomination sewed up. She could loose to Romney but with Trump running as a third party candidate, he will not get enough votes.